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Protein kinase Casein Kinase 2 alpha (PKCK2), 1-391aa, Human, His tag, E.coli

 Product Data Sheet
Catalog NumberPCK0701
Product NameProtein kinase Casein Kinase 2 alpha (PKCK2), 1-391aa, Human, His tag, E.coli
Full NameCasein kinase II alpha 1 subunit isoform a
NCBI Accession No.NP_001886
DescriptionProtein Kinase Casein Kinase 2 (PKCK2, also called CK2) is a ubiquitous Ser/Thr kinase expressed in all eukaryotes. PKCK2 is a tetramer composed of two catalytic kinase domains, alpha subunits, and two identical regulatory beta subunits. It has been implicated in cell cycle control , DNA repair, regulation of the circadian rhythm, and other cellular processes. Recombinant human PKCK2, fused to His tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Molecular Weight47.3 kDa (411 aa), confirmed by MALDI-TOF.
Purification> 90% by SDS - PAGE
Concentration1 mg/ml (determined by Bradford assay)
FormLiquid . 20mM Tris pH8.0 , 500mM NaCl, 1mM DTT, 50% glycerol
StorageCan be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
General ReferenceKim YK., et al. (2006) J Biol Chem. 281(48):36752-7.
Research CategorySignal Transduction,Cancer,Proteases &Inhibitors
PDF Brochure PCK0701.pdf

 *** For research use only. This product is not intended or approved for human, diagnostics or veterinary use.